Intraoperative electrochemotherapy of colorectal liver metastases: A prospective phase II study
نویسندگان
چکیده
منابع مشابه
Intraoperative electrochemotherapy of colorectal liver metastases.
BACKGROUND AND OBJECTIVES Electrochemotherapy is effective in treatment of various cutaneous tumors and could be translated into treatment of deep-seated tumors. With this aim a prospective pilot study was conducted to evaluate feasibility, safety, and efficacy of intraoperative electrochemotherapy in the treatment of colorectal liver metastases. METHODS Electrochemotherapy with bleomycin was...
متن کاملHistopathological findings in colorectal liver metastases after electrochemotherapy
Electrochemotherapy of colorectal liver metastases has been proven to be feasible, safe and effective in a phase I/II study. In that study, a specific group of patients underwent two-stage operation, and the detailed histopathological evaluation of the resected tumors is presented here. Regressive changes in electrochemotherapy-treated liver metastases were evaluated after the second operation ...
متن کاملElectrochemotherapy of colorectal liver metastases - an observational study of its effects on the electrocardiogram
BACKGROUND Electrochemotherapy (ECT) is a combined treatment in which high voltage electroporation (EP) pulses are used to facilitate the uptake of a chemotherapeutic drug into tumor cells, thus increasing antitumor effectiveness of the drug. The effect of ECT of deep-seated tumors located close to the heart on functioning of the heart has not been previously investigated. In this study, we inv...
متن کاملHepatic resection for colorectal liver metastases: prospective study.
OBJECTIVE To assess the operative and long-term survival outcomes of hepatic resection for colorectal liver metastases during an 11-year period in a tertiary referral centre in Hong Kong. DESIGN Prospective study. SETTING University teaching hospital, Hong Kong. SUBJECTS AND METHODS Between January 1989 and December 1999, 72 patients underwent hepatic resection for colorectal liver metast...
متن کاملPatient variability in intraoperative ultrasonographic characteristics of colorectal liver metastases.
OBJECTIVE To determine the distribution of echogenicity (hypoechoic, isoechoic, or hyperechoic) and predominant intraoperative ultrasonography (IOUS) echogenic appearance of colorectal liver metastasis. The interpatient and intrapatient variability of tumor IOUS echogenicity was assessed. DESIGN Retrospective review of prospectively collected database. SETTING Tertiary cancer center. PATI...
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ژورنال
عنوان ژورنال: European Journal of Surgical Oncology
سال: 2020
ISSN: 0748-7983
DOI: 10.1016/j.ejso.2020.04.037